SCHEMBL9833450

SCHEMBL9833450

C=C(C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9830108 0.91 REN (1.00) REN
SCHEMBL9832609 0.83 REN (0.71) REN
SCHEMBL27692377 0.82 REN (0.70) REN
SCHEMBL9876487 0.82 REN (0.70) REN
SCHEMBL10444086 0.79 REN (0.71) REN
SCHEMBL10444511 0.79 REN (0.71) REN
SCHEMBL7364676 0.78 REN (0.67) REN
SCHEMBL10672536 0.78 REN (0.66) REN
SCHEMBL7363470 0.78 REN (0.66) REN
SCHEMBL10460233 0.77 REN (0.63) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258289-A4 PEPTIDE ANALOGS 1991-01-02 EP disclosed
EP-0258289-A1 PEPTIDE ANALOGS ABBOTT LABORATORIES (US) 1988-03-09 EP disclosed
WO-1987004349-A1 PEPTIDE ANALOGS DELLARIA JOSEPH 1987-07-30 WO disclosed