Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.65 |
| ▸ | KDM5A | P29375 | 4/20 | 0.65 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.65 |
| ▸ | KDM4A | O75164 | 3/20 | 0.65 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836494 | 1.00 | ALOX5 (0.72) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL9836200 | 0.98 | ALOX5 (0.74) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL28147120 | 0.94 | ALOX5 (0.72) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL9834381 | 0.94 | ALOX5 (0.77) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL14553382 | 0.86 | ALOX5 (0.79) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL9833833 | 0.84 | ALOX5 (1.00) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL11135720 | 0.84 | KCNH2 (0.60) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL10692283 | 0.83 | ALOX5 (0.79) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL10695268 | 0.81 | ALOX5 (1.00) | ALOX5KDM4CKDM5APHF8KDM4A | |
| SCHEMBL9546190 | 0.80 | ALOX5 (0.49) | ALOX5KDM4CKDM5APHF8KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |