Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 6/20 | 0.68 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | PARG | Q86W56 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834758 | 0.91 | RB1 (0.83) | RB1NR2E1HTR6PARGTBXA2R | |
| SCHEMBL1427264 | 0.91 | RB1 (0.83) | RB1NR2E1HTR6PARGTBXA2R | |
| SCHEMBL4803895 | 0.80 | NR2E1 (0.61) | RB1NR2E1HTR1AHTR1DHTR1B | |
| SCHEMBL14693721 | 0.78 | NR2E1 (0.56) | RB1NR2E1HTR1AHTR1DHTR1B | |
| SCHEMBL23875579 | 0.78 | NR2E1 (0.58) | RB1NR2E1HTR1AHTR1DHTR1B | |
| Sulfuric Acid SCHEMBL7589746 | 0.75 | NR2E1 (0.47) | RB1NR2E1HTR1AHTR1DHTR1B | |
| SCHEMBL9834014 | 0.75 | RB1 (0.59) | RB1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL7406266 | 0.74 | NR2E1 (0.55) | RB1NR2E1HTR1AHTR1DHTR1B | |
| SCHEMBL7406063 | 0.74 | RB1 (0.81) | RB1NR2E1 | |
| SCHEMBL7416460 | 0.74 | RB1 (0.57) | RB1NR2E1HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015711-B | Cycloalkaho [1,2-b] indole-sulphonamides | BAYER AG (DE) | 1992-03-04 | — | — | CN | disclosed |
| EP-0242518-B1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| CN-87100773-A | Cycloalkanes is [1,2-b] indoles-sulfamide compound also | — | 1987-09-02 | — | — | CN | disclosed |