Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833860 | 1.00 | CDK2 (0.70) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22749158 | 0.88 | CDK2 (0.74) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18735896 | 0.86 | CDK2 (0.74) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12443115 | 0.82 | CDK2 (0.58) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6825490 | 0.82 | CDK2 (0.58) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15312914 | 0.81 | MEN1 (0.60) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10118539 | 0.81 | MEN1 (0.60) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22624828 | 0.80 | CDK2 (0.56) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13304088 | 0.80 | MAPT (0.55) | CDK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13256735 | 0.79 | MAPT (0.52) | CDK2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283035-B1 | BENZOXAZOLE DERIVATIVES AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4948900-A | INTERMEDIATES FOR DIABETES THERAPEUTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4897393-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0283035-A1 | Benzoxazole derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |