Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749158 | 0.89 | CDK2 (0.74) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL18735897 | 0.87 | CDK2 (0.57) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL9833864 | 0.86 | CDK2 (0.70) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL9833860 | 0.86 | CDK2 (0.70) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL22624828 | 0.83 | CDK2 (0.56) | CDK2MAOAMAOBMAPTKDM4E | |
| SCHEMBL14337523 | 0.78 | G6PD (0.60) | CDK2MAOBG6PDMAPTKDM4E | |
| SCHEMBL11718823 | 0.77 | MAPT (0.58) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL11718830 | 0.77 | MAPT (0.58) | CDK2MAOAMAOBG6PDMAPT | |
| SCHEMBL9176249 | 0.77 | G6PD (0.60) | CDK2MAOBG6PDMAPTKDM4E | |
| SCHEMBL9173534 | 0.77 | ALDH1A1 (0.67) | CDK2MAOBG6PDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170100414-A1 | SMALL MOLECULE EFFLUX PUMP INHIBITORS | UNIVERSITY OF ROCHESTER (US) | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170100414-A1 | SMALL MOLECULE EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, ABCC1 | CDK2 4648/4885MAOA 3340/4885MAOB 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.