Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647043 | 0.82 | EPHX1 (0.55) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL2659503 | 0.82 | EPHX1 (0.55) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL25334126 | 0.80 | EPHX1 (0.51) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL12764126 | 0.80 | EPHX1 (0.53) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL25954315 | 0.79 | EPHX1 (0.53) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL11038274 | 0.79 | EPHX1 (0.55) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL25333155 | 0.79 | EPHX1 (0.52) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL27813254 | 0.77 | ACHE (0.56) | NPC1RAB9A | |
| SCHEMBL6814639 | 0.77 | ACHE (0.56) | NPC1RAB9A | |
| SCHEMBL21088372 | 0.77 | HDAC1 (0.67) | EPHX1NPC1SMN1; SMN2ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437508-A4 | NON-PEPTIDE RENIN INHIBITORS | — | 1991-11-06 | — | — | EP | disclosed |