Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833381 | 0.94 | MAPT (0.40) | TP53MAPTPTGS1PTGS2RAB9A | |
| SCHEMBL9833062 | 0.94 | TP53 (0.41) | TP53MAPTCNR1ALDH1A1LMNA | |
| SCHEMBL9316562 | 0.93 | TP53 (0.46) | TP53MAPTALDH1A1LMNAIKBKB | |
| SCHEMBL9316088 | 0.92 | TP53 (0.44) | TP53MAPTALDH1A1LMNAIKBKB | |
| SCHEMBL9831814 | 0.90 | TP53 (0.41) | TP53MAPTPTGS1PTGS2RAB9A | |
| SCHEMBL9833737 | 0.90 | TP53 (0.45) | TP53MAPTALDH1A1LMNAIKBKB | |
| SCHEMBL9832532 | 0.90 | ALDH1A1 (0.42) | TP53MAPTCNR1ALDH1A1LMNA | |
| SCHEMBL9832103 | 0.89 | MAPT (0.43) | TP53MAPTCNR1LMNAPTGS1 | |
| SCHEMBL9833948 | 0.89 | ALDH1A1 (0.40) | TP53MAPTCNR1ALDH1A1LMNA | |
| SCHEMBL9832082 | 0.88 | MAPT (0.39) | TP53MAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274443-B1 | HETEROARYL 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-05-29 | — | — | EP | disclosed |
| US-4816467-A | BACTERICIDES, VIRICIDES | FARMITALIA CARLO ERBA S.R.L (IT) | 1989-03-28 | — | — | US | disclosed |