Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036388 | 0.74 | KMT2A (0.74) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL9734501 | 0.73 | KDM4E (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL17049187 | 0.73 | KDM4E (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL3063794 | 0.71 | ESR2 (0.44) | KMT2AMEN1ESR1ESR2 | |
| SCHEMBL5120484 | 0.70 | SLC6A2 (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| Hydrochloric Acid SCHEMBL11841746 | 0.69 | POLB (0.35) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL5129678 | 0.68 | KMT2A (0.47) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL16153700 | 0.67 | MAPT (0.76) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL8050780 | 0.67 | MEN1 (0.55) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL7950190 | 0.66 | MEN1 (0.58) | KMT2AMAPTALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156261-B1 | FLUOROGENIC DIHYDROQUINOLONE AND DIHYDROCOUMARIN INDICATORS FOR HYDROGEN PEROXIDE | MILES INC. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4794079-A | PEROXIDASE | MILES INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |