Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116383 | 0.85 | PPARG (0.48) | MEN1ALDH1A1KMT2APPARGPPARA | |
| SCHEMBL28999667 | 0.85 | PPARG (0.54) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL13520076 | 0.83 | PPARG (0.60) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL9968951 | 0.80 | HSD17B1 (0.45) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL14038361 | 0.79 | ESR2 (0.41) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL31562259 | 0.77 | CYP4F2 (0.49) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10635452 | 0.75 | ESR1 (0.48) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL8036388 | 0.75 | KMT2A (0.74) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL17049187 | 0.74 | KDM4E (0.50) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL14378544 | 0.73 | FFAR1 (0.45) | KDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081044-A | Detection of hydrogen peroxide with optical indicator chalcogen compounds | MILES INC. (US) | 1992-01-14 | — | — | US | disclosed |
| US-4996332-A | On oxidation produce fluorescent signals in analytical systems | MILES INC. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4778893-A | FLUORESCENT; OXIDATION OF CHALCOGENS WITH HYDROGEN PEROXIDE | MILES INC. (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0121743-B1 | OPTICAL INDICATOR CHALCOGEN COMPOUNDS AND USE | MILES LABORATORIES, INC. (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |