Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29541078 | 0.67 | IDO1 (0.32) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL607872 | 0.63 | TDP2 (0.37) | CCNA2CDK2PTPRCCTSLCTSS | |
| SCHEMBL1749823 | 0.60 | GAA (0.50) | CCNA2CDK2PTPRCCTSLCTSS | |
| SCHEMBL27347509 | 0.59 | TDP2 (0.65) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL27837605 | 0.58 | — | — | |
| SCHEMBL10434480 | 0.58 | TDP2 (0.49) | CCNA2CDK2PTPRCCTSLCTSS | |
| SCHEMBL27346575 | 0.57 | PTPRC (0.71) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL5093999 | 0.55 | TDP2 (0.38) | CCNA2CDK2PTPRCCTSLCTSS | |
| SCHEMBL9694568 | 0.55 | GAA (0.38) | CCNA2CDK2PTPRCCTSLCTSS | |
| SCHEMBL2299734 | 0.55 | CCNA2 (0.40) | CCNA2CDK2PTPRCCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229823-B1 | POLYCYCLIC QUINOLINE, NAPHTHYRIDINE AND PYRAZINOPYRIDINE DERIVATIVES | SCHERING CORPORATION (US) | 1991-09-25 | — | — | EP | disclosed |