Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.65 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.63 |
| ▸ | PDXK | O00764 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834681 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL3442736 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL3442735 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9836549 | 0.82 | TRIM24 (0.59) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9836547 | 0.82 | TRIM24 (0.59) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL29906 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL5934767 | 0.78 | KDM4E (0.82) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL8533734 | 0.78 | KDM4E (0.97) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL5416120 | 0.78 | KDM4E (0.97) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL50601 | 0.78 | TRIM24 (1.00) | KDM4EALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |