Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PDXK | O00764 | 1/20 | 0.58 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442735 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9836547 | 0.99 | TRIM24 (0.59) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9836549 | 0.99 | TRIM24 (0.59) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL9834684 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL9834681 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL14687792 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL14687791 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9837034 | 0.75 | CA12 (0.49) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| Pyridoxal SCHEMBL29906 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL5934767 | 0.73 | KDM4E (0.82) | KDM4EALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812037-B2 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL, INC. (BB) | 2010-10-12 | — | — | US | disclosed |
| EP-1817288-A4 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INT INC (BB) | 2009-08-26 | — | — | EP | disclosed |
| EP-1817288-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | Medicure International Inc. (BB) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006050598-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-18 | — | — | WO | disclosed |
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | PNPO, PLPBP, PRDX6 | KDM4E 2636/4885ALDH1A1 1337/4885LMNA 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.