Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834934 | 1.00 | CA1 (0.47) | CA1CA2CA5ACA9NPC1 | |
| SCHEMBL10501861 | 0.91 | NPC1 (0.46) | CA1CA2CA5ACA9NPC1 | |
| SCHEMBL11131057 | 0.91 | CA1 (0.44) | CA1CA2CA5ACA9NPC1 | |
| SCHEMBL10568557 | 0.90 | CA1 (0.43) | CA1CA2CA5ACA9NPC1 | |
| SCHEMBL9684536 | 0.89 | NPC1 (0.42) | CA1CA2CA5ACA9NPC1 | |
| Sulfometuron Methyl SCHEMBL54998 | 0.86 | GAA (0.50) | CA1CA2CA5ACA9NPC1 | |
| Sulfometuron Methyl SCHEMBL9137833 | 0.86 | GAA (0.50) | CA1CA2CA5ACA9NPC1 | |
| Sulfometuron Methyl SCHEMBL27545620 | 0.86 | GAA (0.50) | CA1CA2CA5ACA9NPC1 | |
| Sulfometuron Methyl SCHEMBL15524982 | 0.85 | GAA (0.49) | CA1CA2CA5ACA9NPC1 | |
| SCHEMBL9763398 | 0.84 | ALDH1A1 (0.45) | CA1CA2CA5ACA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | claimed |
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |