SCHEMBL9834992

SCHEMBL9834992

CCN1CC(=O)N(CC)CC1=O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.38
ELANE P08246 1/20 0.38
CTSG P08311 1/20 0.38
CTRC Q99895 1/20 0.38
ACHE P22303 2/20 0.35
P2RX7 Q99572 2/20 0.34
GMNN O75496 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MGLL Q99685 1/20 0.33
INMT O95050 1/20 0.31
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19546254 1.00 F2 (0.38) F2ELANECTSGCTRCACHE
SCHEMBL14423078 0.97
SCHEMBL16196108 0.87 L3MBTL1 (0.39) F2ELANECTSGCTRCACHE
SCHEMBL15896894 0.87 PIK3CD (0.35) F2ELANECTSGCTRCACHE
SCHEMBL19546266 0.87 PIK3CD (0.35) F2ELANECTSGCTRCACHE
SCHEMBL19546268 0.87 PIK3CD (0.35) F2ELANECTSGCTRCACHE
SCHEMBL19545972 0.87 PIK3CD (0.35) F2ELANECTSGCTRCACHE
Ether SCHEMBL27741444 0.84 F2 (0.32) F2ELANECTSGCTRCLMNA
SCHEMBL16196098 0.82 MAPT (0.32) MAPTPIK3CD
SCHEMBL19275178 0.82 CYP3A4 (0.38) MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US claimed
US-9341949-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2016-05-17 US claimed
US-20140322647-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2014-10-30 US claimed
WO-2023242598-A1 BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LIMITED (GB) 2023-12-21 WO disclosed
US-11537045-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2022-12-27 US disclosed
EP-4045564-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF Promerus, LLC (US) 2022-08-24 EP disclosed
CN-114555674-A Photosensitive composition and application thereof 普罗米鲁斯有限责任公司 2022-05-27 CN disclosed
US-20210116807-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2021-04-22 US disclosed
WO-2021076131-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2021-04-22 WO disclosed
US-9696623-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2017-07-04 US disclosed
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US disclosed
WO-2014113485-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. (US) 2014-07-24 WO disclosed
US-20090239873-A1 Phenyl-piperazine derivatives as modulators of muscarinic receptors BLANCO MIGUEL GARCIA-GUZMAN 2009-09-24 US disclosed
US-7563795-B2 Phenyl-piperazine derivatives as modulators of muscarinic receptors VERTEX PHARMACEUTICALS INCORPORATED (US) 2009-07-21 US disclosed
EP-0216745-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED AMINOMETHYLPHOSPHONIC ACIDS Monsanto Company (US) 1991-10-16 EP disclosed
EP-0216744-B1 THE COMPOUND 1,4-DIISOPROPYL-2,5-DIKETOPIPERAZINE Monsanto Company (US) 1991-08-14 EP disclosed
US-4804499-A Process for the preparation of N-substituted aminomethylphosphonic acids MONSANTO COMPANY (US) 1989-02-14 US disclosed
US-4694082-A CHEMICAL INTERMEDIATE FOR HERBICIDE MONSANTO COMPANY (US) 1987-09-15 US disclosed
EP-0216744-A2 The compound 1,4-diisopropyl-2,5-diketopiperazine Monsanto Company (US) 1987-04-01 EP disclosed
EP-0216745-A1 Process for the preparation of N-substituted aminomethylphosphonic acids Monsanto Company (US) 1987-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239873-A1 Phenyl-piperazine derivatives as modulators of muscarinic receptors CHRM3, CHRM5, CHRM2 F2 4698/4885ELANE 4120/4885CTSG 3431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.