Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824776 | 0.81 | TSHR (0.56) | TSHRPOLBALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL10473579 | 0.80 | TSHR (0.35) | TSHRL3MBTL1POLBALDH1A1USP2 | |
| SCHEMBL10396216 | 0.80 | TSHR (0.35) | TSHRL3MBTL1POLBALDH1A1USP2 | |
| SCHEMBL10397567 | 0.80 | TSHR (0.40) | TSHRPOLBALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL8374481 | 0.78 | TSHR (0.36) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9831411 | 0.78 | ALDH1A1 (0.41) | TSHRL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10663596 | 0.77 | TSHR (0.43) | TSHRPOLBALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL10397326 | 0.76 | TSHR (0.44) | TSHRALDH1A1USP2KMT2A | |
| SCHEMBL8355381 | 0.74 | NFKBIA (0.40) | TSHRPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7848907 | 0.74 | MEN1 (0.37) | L3MBTL1POLBALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |