Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094361 | 0.82 | CYP19A1 (0.56) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL7153929 | 0.82 | CYP19A1 (0.56) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL7294129 | 0.82 | CYP19A1 (0.56) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL6592452 | 0.78 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL697520 | 0.76 | CYP19A1 (0.57) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL18415628 | 0.76 | CYP19A1 (0.61) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL7605652 | 0.74 | MAOB (0.48) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL10916938 | 0.74 | MAOB (0.48) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL7241604 | 0.74 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL2381366 | 0.74 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161218-B1 | BENZO-(PYRANO AND THIOPYRANO)PYRIDINES | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| EP-0161218-A2 | Benzo-(pyrano and thiopyrano)pyridines | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |