Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453454 | 0.90 | TDP1 (0.39) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9836602 | 0.83 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL10453185 | 0.82 | TDP1 (0.40) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9833447 | 0.82 | TSHR (0.37) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9836252 | 0.81 | HTT (0.36) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL10452248 | 0.81 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9835035 | 0.79 | TDP1 (0.40) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9835821 | 0.79 | TP53 (0.34) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9835486 | 0.78 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL10363972 | 0.77 | MAPT (0.34) | TDP1TSHRCYP3A4MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |