Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453485 | 0.90 | TSHR (0.35) | TSHRCYP3A4TDP1MAPK1GAA | |
| SCHEMBL9835299 | 0.82 | TDP1 (0.40) | TSHRCYP3A4TDP1MAPK1MEN1 | |
| SCHEMBL10453219 | 0.81 | TSHR (0.39) | TSHRCYP3A4TDP1MAPK1GAA | |
| SCHEMBL9835392 | 0.80 | POLB (0.32) | TSHRCYP3A4TDP1MAPK1GAA | |
| SCHEMBL9836602 | 0.80 | TDP1 (0.43) | TSHRCYP3A4TDP1MAPK1GAA | |
| SCHEMBL10452416 | 0.77 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL9835887 | 0.77 | CYP3A4 (0.37) | TSHRCYP3A4MEN1KMT2APOLB | |
| SCHEMBL9835035 | 0.73 | TDP1 (0.40) | TSHRCYP3A4TDP1MAPK1MEN1 | |
| SCHEMBL10453454 | 0.72 | TDP1 (0.39) | TSHRCYP3A4TDP1MAPK1MEN1 | |
| SCHEMBL9835486 | 0.71 | TDP1 (0.41) | TSHRCYP3A4TDP1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |