Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 8/20 | 0.71 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.71 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.71 |
| ▸ | KDM5C | P41229 | 1/20 | 0.68 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.68 |
| ▸ | KDM4A | O75164 | 2/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.63 |
| ▸ | PPARG | P37231 | 6/20 | 0.63 |
| ▸ | PPARD | Q03181 | 6/20 | 0.63 |
| ▸ | PPARA | Q07869 | 6/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834650 | 0.96 | KDM4C (0.76) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL31749305 | 0.88 | KDM4C (0.69) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL9512967 | 0.88 | KDM4C (0.69) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL8450995 | 0.88 | KDM4C (0.69) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL10439922 | 0.87 | KDM4C (0.71) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL3328620 | 0.86 | KDM4C (0.66) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL9837192 | 0.85 | KDM5A (0.57) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL10387789 | 0.84 | KDM4C (0.64) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL1759037 | 0.83 | GPR84 (0.65) | KDM5AKDM4CPHF8GPR84PPARG | |
| SCHEMBL15480451 | 0.82 | GPR84 (0.71) | KDM5AKDM4CPHF8GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |