Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835697 | 1.00 | KMT2A (0.59) | KMT2AMAPTPLA2G4AGPR84PPARG | |
| SCHEMBL19171953 | 0.77 | KMT2A (0.83) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL670146 | 0.77 | LMNA (0.43) | KMT2AGPR84HDAC11TSHRFABP4 | |
| SCHEMBL10071357 | 0.77 | KMT2A (0.83) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL23804131 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL19816485 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL7824955 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL25287634 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL6839108 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL561348 | 0.76 | KMT2A (1.00) | KMT2AMAPTGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |