Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021891 | 0.90 | CYP2D6 (0.36) | CYP2D6CYP2C19KDM4E | |
| SCHEMBL4880055 | 0.84 | CYP2D6 (0.44) | CYP2D6CYP2C19 | |
| SCHEMBL5358112 | 0.80 | CYP2D6 (0.42) | CYP2D6CYP2C19 | |
| SCHEMBL5079078 | 0.78 | CYP2D6 (0.37) | CYP2D6CYP2C19KDM4E | |
| SCHEMBL5352866 | 0.76 | CYP2D6 (0.45) | CYP2D6CYP2C19 | |
| SCHEMBL3021932 | 0.76 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL5837266 | 0.74 | CYP2D6 (0.34) | CYP2D6CYP2C19KDM4E | |
| SCHEMBL5359953 | 0.73 | CYP2D6 (0.40) | CYP2D6CYP2C19 | |
| SCHEMBL5836624 | 0.73 | CYP2D6 (0.35) | CYP2D6CYP2C19 | |
| SCHEMBL5073008 | 0.72 | PTGS1 (0.36) | CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009578-A1 | Use Of A Combination Chain Transfer And Activating Agent To Control Molecular Weight And Optical Density Of Pd Catalyzed Norbornene Polymers | PROMERUS LLC (US) | 2011-01-13 | — | — | US | disclosed |
| US-7759439-B2 | Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers | PROMERUS LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080242810-A1 | Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers | PROMERUS LLC (US) | 2008-10-02 | — | — | US | disclosed |