Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 3/20 | 0.33 |
| ▸ | ATP4B | P51164 | 3/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.30 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643701 | 0.88 | SARM1 (0.47) | AGXTSARM1ATP4AATP4BNUDT1 | |
| SCHEMBL8910240 | 0.77 | AGXT (0.49) | AGXTSARM1ATP4AATP4BLNPEP | |
| SCHEMBL1060082 | 0.77 | AGXT (0.66) | AGXTSARM1ATP4AATP4BFTO | |
| SCHEMBL29382857 | 0.77 | AGXT (0.66) | AGXTSARM1ATP4AATP4BFTO | |
| Hydrochloric Acid SCHEMBL3247161 | 0.75 | AGXT (0.64) | AGXTSARM1ATP4AATP4BFTO | |
| SCHEMBL8500701 | 0.73 | AGXT (0.45) | AGXTSARM1ATP4AATP4BLNPEP | |
| SCHEMBL6740782 | 0.73 | NPC1 (0.40) | SARM1ATP4AATP4BWDR5KMT2A | |
| SCHEMBL3182871 | 0.72 | AGXT (0.44) | AGXTATP4AATP4BLNPEPPDE10A | |
| SCHEMBL9793484 | 0.72 | AGXT (0.44) | AGXTATP4AATP4BPDE10AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL8977353 | 0.71 | SARM1 (0.46) | AGXTSARM1ATP4AATP4BAGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233760-B1 | SULFENAMIDE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0174726-B1 | PYRIDINE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |
| US-4769456-A | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0233760-A1 | Sulfenamide derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |
| US-4689333-A | ANTIULCER AGENTS, CASTRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-25 | — | — | US | disclosed |
| US-4628098-A | Including Prevacid (TM) lansoprazole, 2-(3-methyl-4-(2,2,2-trifluoroethoxy)-5-methyl-pyrid-2 -yl)methylsulfinylbenzimidazole; proton pump inhibitors, antiulcer, antisecretory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
| EP-0174726-A1 | Pyridine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-03-19 | — | — | EP | disclosed |