Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964625 | 0.90 | GABRA1 (0.38) | MAPK1TDP1GABRA1GABRB2TSHR | |
| SCHEMBL1019709 | 0.85 | MAPK1 (0.45) | MAPK1TDP1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL1952585 | 0.84 | MAPK1 (0.38) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL28565932 | 0.81 | GABRA1 (0.36) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL3388964 | 0.81 | GABRA1 (0.32) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL17648937 | 0.80 | GABRA1 (0.33) | GABRA1GABRB2ALDH1A1CYP3A4TSHR | |
| SCHEMBL28565654 | 0.78 | KDM4E (0.38) | MAPK1TDP1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL10611282 | 0.78 | GABRA1 (0.50) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL28912552 | 0.78 | MAPK1 (0.34) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL1950823 | 0.77 | MAPK1 (0.42) | MAPK1TDP1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248506-A | Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-107001372-B | Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2021-04-27 | — | — | CN | disclosed |
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0241559-A1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-10-21 | — | — | EP | disclosed |