Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835853 | 1.00 | GAA (0.54) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10416580 | 0.90 | GAA (0.51) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10416581 | 0.90 | GAA (0.51) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10501740 | 0.90 | GAA (0.51) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10517445 | 0.90 | SMN1; SMN2 (0.49) | GAALMNAALDH1A1KDM4ESMN1; SMN2 | |
| Sulfuric Acid SCHEMBL11101202 | 0.88 | GAA (0.49) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10498990 | 0.87 | LMNA (0.48) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL9763671 | 0.87 | GAA (0.48) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL9833657 | 0.86 | GAA (0.47) | GAALMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL9833662 | 0.86 | GAA (0.47) | GAALMNAALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |