Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836952 | 0.76 | HDAC4 (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9835850 | 0.71 | ALDH1A1 (0.32) | ALDH1A1GSTP1 | |
| SCHEMBL3421768 | 0.69 | GSTP1 (0.33) | GSTP1 | |
| SCHEMBL57575 | 0.67 | GSTP1 (0.32) | GSTP1 | |
| SCHEMBL9004436 | 0.67 | HDAC2 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28593099 | 0.65 | HDAC2 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9300220 | 0.65 | GSTP1 (0.31) | GSTP1 | |
| SCHEMBL18857348 | 0.65 | HDAC4 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL301811 | 0.64 | GSTP1 (0.40) | ALDH1A1GSTP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9837482 | 0.64 | GSTP1 (0.32) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210637-B1 | OPTICAL COATING COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4814257-A | PHOTOHARDENING ACRYLATE ESTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0210637-A2 | Optical coating composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |