SCHEMBL9836232

SCHEMBL9836232

CC=C(C)C(OC(=O)Nc1cc(C(F)(F)F)ccc1Cl)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
KMT2A Q03164 6/20 0.47
MEN1 O00255 5/20 0.47
MAPT P10636 3/20 0.47
CYP2C19 P33261 4/20 0.45
CYP1A2 P05177 4/20 0.45
CYP2D6 P10635 3/20 0.45
MAPK1 P28482 1/20 0.45
CYP3A4 P08684 3/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 4/20 0.44
TP53 P04637 1/20 0.44
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836642 0.90 KMT2A (0.48) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL9836242 0.90 KMT2A (0.47) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL27676769 0.87 KMT2A (0.49) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL9837008 0.83 L3MBTL1 (0.48) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL9837102 0.78 KMT2A (0.49) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL27315903 0.78 KMT2A (0.56) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL27325179 0.77 KMT2A (0.50) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL20713793 0.77 MEN1 (0.57) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL27389687 0.75 L3MBTL1 (0.48) L3MBTL1KMT2AMEN1MAPTCYP2C19
SCHEMBL9834379 0.75 MAPT (0.52) L3MBTL1KMT2AMEN1MAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed