Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536523 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL2829363 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL428254 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL424593 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL536460 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL428393 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL425246 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL28496264 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| SCHEMBL489813 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ELMNAALOX15 | |
| Citric Acid SCHEMBL4292973 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |