SCHEMBL9836394

SCHEMBL9836394

CCCC(Cn1cncn1)(OC(C)C)c1ccc(Cl)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 3/20 0.39
PKM P14618 1/20 0.39
CYP2C9 P11712 6/20 0.38
CYP2C19 P33261 6/20 0.38
CYP1A2 P05177 3/20 0.38
CYP2D6 P10635 3/20 0.38
KCNH2 Q12809 2/20 0.38
THRB P10828 1/20 0.37
KMT2A Q03164 2/20 0.37
CYP2B6 P20813 1/20 0.36
CYP3A5 P20815 1/20 0.36
CYP3A7 P24462 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP3A43 Q9HB55 1/20 0.36
CYP46A1 Q9Y6A2 1/20 0.36
MEN1 O00255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835295 0.88 CYP3A4 (0.42) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL9835078 0.87 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL10364012 0.86 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL10364903 0.81 CYP3A4 (0.40) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL9835425 0.81 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL9836134 0.80 CYP3A4 (0.39) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL2435556 0.78 CYP3A4 (0.49) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL9835885 0.78 CYP3A4 (0.38) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL17223582 0.78 CYP3A4 (0.40) CYP3A4ALDH1A1LMNAPKMCYP2C9
SCHEMBL15824213 0.78 CYP3A4 (0.40) CYP3A4ALDH1A1LMNAPKMCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0126430-B1 PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE CIBA-GEIGY AG (CH) 1991-08-28 EP disclosed
US-4945100-A Process for the preparation of 1-triazolylethyl ether derivatives CIBA-GEIGY CORPORATION (US) 1990-07-31 US disclosed
EP-0126430-A2 Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use CIBA-GEIGY AG (CH) 1984-11-28 EP disclosed