SCHEMBL10364012

SCHEMBL10364012

CCCOC(CCC)(Cn1cncn1)c1ccc(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 2/20 0.36
HTT P42858 1/20 0.36
CYP2C9 P11712 5/20 0.36
CYP2C19 P33261 5/20 0.36
HSP90AA1 P07900 2/20 0.36
MEN1 O00255 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
ADRA1A P35348 1/20 0.36
CYP51A1 Q16850 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2D6 P10635 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835078 0.92 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL9836134 0.92 CYP3A4 (0.39) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL9833615 0.90 CYP3A4 (0.39) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL10365000 0.89 CYP3A4 (0.46) CYP3A4ALDH1A1LMNAKMT2AKDM4E
SCHEMBL9835295 0.89 CYP3A4 (0.42) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL10364903 0.89 CYP3A4 (0.40) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL9836394 0.86 CYP3A4 (0.40) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL9835885 0.85 CYP3A4 (0.38) CYP3A4ALDH1A1LMNAPKMKMT2A
SCHEMBL9834040 0.82 ALDH1A1 (0.39) CYP3A4ALDH1A1LMNAKMT2ATHRB
SCHEMBL9835425 0.81 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0082340-B1 MICROBICIDAL TRIAZOLYL-ETHYL-ETHERS CIBA-GEIGY AG (CH) 1990-01-03 EP disclosed
EP-0082340-A1 Microbicidal triazolyl-ethyl-ethers CIBA-GEIGY AG (CH) 1983-06-29 EP disclosed