SCHEMBL983662

SCHEMBL983662

Cc1ccc(OC(=O)O)c(C)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
NCEH1 Q6PIU2 2/20 0.44
POLB P06746 1/20 0.39
TDP2 O95551 1/20 0.35
NSD2 O96028 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PAX8 Q06710 1/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MCL1 Q07820 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16585755 0.88 PTPN1 (0.50) PTPN1NCEH1POLBKDM4EALDH1A1
SCHEMBL729665 0.84 NCEH1 (0.46) PTPN1NCEH1POLBTDP2NSD2
SCHEMBL29580838 0.84 NCEH1 (0.46) PTPN1NCEH1POLBTDP2NSD2
SCHEMBL5588933 0.83 NCEH1 (0.42) PTPN1NCEH1POLBKDM4EALDH1A1
SCHEMBL6973179 0.83 NCEH1 (0.44) PTPN1NCEH1POLBTDP2NSD2
SCHEMBL6269458 0.83 PTPN1 (0.57) PTPN1NCEH1POLBKDM4EALDH1A1
SCHEMBL28061093 0.83 MAPT (0.44) POLBKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1837507 0.81 POLB (0.57) POLBKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1834206 0.81 NCEH1 (0.43) PTPN1NCEH1POLBTDP2NSD2
SCHEMBL30409286 0.81 NCEH1 (0.43) PTPN1NCEH1POLBTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-2540697-B1 METHOD FOR PRODUCING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2022-04-20 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
US-20200048405-A1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE POLYMER AND ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-13 US disclosed
EP-2275405-B1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2019-04-24 EP disclosed
EP-2275406-B1 PROCESS FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2018-11-28 EP disclosed
EP-3153499-B1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2018-09-19 EP disclosed
EP-2322504-B9 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2017-09-06 EP disclosed
EP-1641733-A2 METHOD AND APPARATUS FOR PRODUCTION OF ALKYL ARYL ETHER AND DIARYL CARBONATE General Electric Company A Corporation of the State of New York (US) 2006-04-05 EP disclosed
WO-2005000776-A2 METHOD AND APPARATUS FOR PRODUCTION OF ALKYL ARYL ETHER AND DIARYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2005-01-06 WO disclosed
US-20040266974-A1 METHOD AND APPARATUS FOR PRODUCTION OF ALKYL ARYL ETHER AND DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2004-12-30 US disclosed
EP-0781760-B1 Continuous manufacturing method for aromatic carbonates GEN ELECTRIC (US) 2002-09-04 EP disclosed
EP-0780361-B1 Manufacturing method for aromatic carbonates GEN ELECTRIC (US) 2000-09-06 EP disclosed
EP-0591923-B1 Continuous production of aromatic carbonates DAICEL CHEM (JP) 1998-08-26 EP disclosed
EP-0781760-A1 Continuous manufacturing method for aromatic carbonates GENERAL ELECTRIC COMPANY (US) 1997-07-02 EP disclosed
EP-0780361-A1 Manufacturing method for aromatic carbonates GENERAL ELECTRIC COMPANY (US) 1997-06-25 EP disclosed
US-5380908-A From alkylaryl carbonates produced from dialkyl carbonates and a phenol, distillation of alcohol DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-01-10 US disclosed
EP-0591923-A1 Continuous production of aromatic carbonates DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-13 EP disclosed