SCHEMBL729665

SCHEMBL729665

Cc1ccc(OC(=O)Oc2ccc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.46
PTPN1 P18031 1/20 0.42
POLB P06746 2/20 0.40
TDP2 O95551 1/20 0.37
NSD2 O96028 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PAX8 Q06710 1/20 0.37
MAPT P10636 1/20 0.36
ACHE P22303 3/20 0.35
HTT P42858 1/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 3/20 0.34
HSD17B10 Q99714 3/20 0.34
GBA1 P04062 1/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580838 1.00 NCEH1 (0.46) NCEH1PTPN1POLBTDP2NSD2
SCHEMBL1834875 0.90 POLB (0.53) NCEH1PTPN1POLBMAPTACHE
SCHEMBL984617 0.90 NCEH1 (0.46) NCEH1PTPN1POLBMAPTACHE
SCHEMBL1839495 0.89 POLB (0.44) NCEH1PTPN1POLBMAPTACHE
SCHEMBL1835094 0.86 TYMS (0.43) NCEH1PTPN1MAPTACHEKDM4E
SCHEMBL6973179 0.84 NCEH1 (0.44) NCEH1PTPN1POLBTDP2NSD2
SCHEMBL6269458 0.84 PTPN1 (0.57) NCEH1PTPN1POLBACHEHTT
SCHEMBL983662 0.84 PTPN1 (0.45) NCEH1PTPN1POLBTDP2NSD2
SCHEMBL1838815 0.83 PTPN1 (0.43) NCEH1PTPN1POLBMAPTKDM4E
SCHEMBL1834206 0.83 NCEH1 (0.43) NCEH1PTPN1POLBTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
EP-3838892-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2022-10-12 EP disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-2540697-B1 METHOD FOR PRODUCING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2022-04-20 EP disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed
WO-2005000776-A2 METHOD AND APPARATUS FOR PRODUCTION OF ALKYL ARYL ETHER AND DIARYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2005-01-06 WO disclosed
US-20040266974-A1 METHOD AND APPARATUS FOR PRODUCTION OF ALKYL ARYL ETHER AND DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2004-12-30 US disclosed
EP-0781760-B1 Continuous manufacturing method for aromatic carbonates GEN ELECTRIC (US) 2002-09-04 EP disclosed
EP-0780361-B1 Manufacturing method for aromatic carbonates GEN ELECTRIC (US) 2000-09-06 EP disclosed
EP-0591923-B1 Continuous production of aromatic carbonates DAICEL CHEM (JP) 1998-08-26 EP disclosed
EP-0781760-A1 Continuous manufacturing method for aromatic carbonates GENERAL ELECTRIC COMPANY (US) 1997-07-02 EP disclosed
EP-0780361-A1 Manufacturing method for aromatic carbonates GENERAL ELECTRIC COMPANY (US) 1997-06-25 EP disclosed
US-5380908-A From alkylaryl carbonates produced from dialkyl carbonates and a phenol, distillation of alcohol DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-01-10 US disclosed
EP-0591923-A1 Continuous production of aromatic carbonates DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B NCEH1 1899/4885PTPN1 3433/4885POLB 3507/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B NCEH1 1908/4885PTPN1 3308/4885POLB 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.