Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836698 | 0.87 | MAPT (0.49) | PDE4B | |
| SCHEMBL9836700 | 0.85 | — | — | |
| SCHEMBL9838383 | 0.84 | — | — | |
| SCHEMBL8228061 | 0.84 | PDE4B (0.65) | PDE4B | |
| SCHEMBL1059182 | 0.83 | — | — | |
| SCHEMBL10958297 | 0.82 | PDE4B (0.56) | PDE4B | |
| SCHEMBL1053229 | 0.82 | — | — | |
| SCHEMBL1081414 | 0.81 | — | — | |
| SCHEMBL2457450 | 0.80 | NPC1 (0.61) | PDE4B | |
| SCHEMBL9838441 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180318-B1 | AMIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4745121-A | AMINE OR CARBOXAMIDE SUBSTITUTED | ICI AMERICAS INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0180318-A1 | Amide derivatives | ICI AMERICAS INC. (US) | 1986-05-07 | — | — | EP | disclosed |