Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092045 | 0.87 | — | — | |
| SCHEMBL530785 | 0.83 | — | — | |
| SCHEMBL7735833 | 0.83 | KMT2A (0.39) | KMT2ADPP7SIGMAR1 | |
| SCHEMBL818299 | 0.78 | — | — | |
| SCHEMBL538845 | 0.78 | — | — | |
| SCHEMBL14473427 | 0.76 | DPP7 (0.52) | KMT2ADPP7 | |
| SCHEMBL1485739 | 0.76 | DPP7 (0.52) | KMT2ADPP7 | |
| SCHEMBL7536595 | 0.76 | DPP7 (0.52) | KMT2ADPP7 | |
| SCHEMBL479254 | 0.76 | DPP7 (0.52) | KMT2ADPP7 | |
| SCHEMBL7533868 | 0.76 | DPP7 (0.52) | KMT2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104522-B1 | NEW PYRAZOLO(3,4-B)PYRIDINE DERIVATIVES AND PROCESS FOR PRODUCING THEM | GRUPPO LEPETIT S.p.A. (IT) | 1991-05-29 | — | — | EP | disclosed |
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |
| US-4612318-A | CNS-depressant and analgesic tricyclo-[pyrazolo-[3,4-6]-pyridine] derivatives and pharmaceutical compositions thereof | GRUPPO LEPETIT S.P.A. (IT) | 1986-09-16 | — | — | US | disclosed |
| US-4500525-A | CARDIOTONIC, HYPOTENSIVE, NEUROLEPTIC, ANALGESIC, ANTIINFLAMMATORYAGENTS, AND CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1985-02-19 | — | — | US | disclosed |
| EP-0104522-A2 | New pyrazolo(3,4-b)pyridine derivatives and process for producing them | GRUPPO LEPETIT S.p.A. (IT) | 1984-04-04 | — | — | EP | disclosed |
| EP-0086422-A2 | Pharmacologically active pyrazolo(4,3-c)pyridines | GRUPPO LEPETIT S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |