⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836904 | 0.87 | KMT2A (0.33) | — | |
| SCHEMBL530785 | 0.74 | — | — | |
| SCHEMBL7735833 | 0.74 | KMT2A (0.39) | — | |
| SCHEMBL689663 | 0.71 | — | — | |
| SCHEMBL666631 | 0.71 | — | — | |
| SCHEMBL666686 | 0.71 | — | — | |
| SCHEMBL538845 | 0.70 | — | — | |
| SCHEMBL818299 | 0.70 | — | — | |
| SCHEMBL2093735 | 0.70 | — | — | |
| SCHEMBL6949868 | 0.69 | SIGMAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | claimed |
| US-8163769-B2 | 1,8-naphthyridine derivatives | ABBOTT LABORATORIES (US) | 2012-04-24 | — | — | US | disclosed |
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | disclosed |
| EP-0101829-B1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | DAIICHI SEIYAKU CO., LTD. (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4539401-A | Pyridobenzoxazine derivatives useful as antibacterial agents | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4535161-A | ANTIBIOTIC, BACTERICIDE | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0101829-A2 | Tricyclic compounds, a process for their production and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-03-07 | — | — | EP | disclosed |