Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584377 | 0.78 | BLM (0.66) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9836199 | 0.78 | MEN1 (0.61) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL10046637 | 0.77 | BLM (0.69) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL7120255 | 0.76 | BLM (0.78) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9584362 | 0.76 | BLM (0.71) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL8050648 | 0.74 | PNP (0.65) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| Ganciclovir SCHEMBL10901087 | 0.74 | BLM (0.87) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9585855 | 0.73 | PDE3A (0.75) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL13601896 | 0.73 | MEN1 (0.52) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9068089 | 0.73 | BLM (0.73) | PDE3AMEN1KMT2ABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |