Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PNP | P00491 | 10/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.55 |
| ▸ | POLG | P54098 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660736 | 0.86 | PNP (0.67) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL9836094 | 0.82 | MEN1 (0.55) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL7814355 | 0.81 | MEN1 (0.76) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL11254814 | 0.81 | PNP (0.65) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL29370760 | 0.79 | PNP (0.87) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL8445568 | 0.79 | MEN1 (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL11244147 | 0.78 | MEN1 (0.71) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14501172 | 0.78 | PNP (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14501075 | 0.78 | PNP (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL9836906 | 0.78 | PDE3A (0.53) | MEN1KMT2AHBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |