Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 11/20 | 0.62 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181175 | 0.91 | AKR1B1 (0.65) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10571505 | 0.89 | AKR1B1 (0.62) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL9257211 | 0.87 | AKR1B1 (0.66) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL9255149 | 0.86 | AKR1B1 (0.68) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL9254962 | 0.86 | AKR1B1 (0.68) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL9184546 | 0.86 | AKR1B1 (0.65) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10574757 | 0.86 | AKR1B1 (0.65) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10576515 | 0.86 | AKR1B1 (0.59) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10607407 | 0.81 | AKR1B1 (0.74) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10575326 | 0.80 | AKR1B1 (0.69) | AKR1B1AKR1A1AKR1B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264586-B1 | HYDANTOIN DERIVATIVES FOR TREATING COMPLICATIONS OF DIABETES | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0264586-A1 | Hydantoin derivatives for treating complications of diabetes | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-04-27 | — | — | EP | disclosed |