Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929412 | 0.92 | TDP1 (0.39) | TDP1MAPK1CYP3A4TRPA1KDM1A | |
| SCHEMBL28565939 | 0.89 | TDP1 (0.41) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL10347965 | 0.88 | TDP1 (0.39) | TDP1MAPK1CYP3A4TRPA1KDM1A | |
| SCHEMBL1493025 | 0.84 | TDP1 (0.52) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL1457032 | 0.82 | TDP1 (0.56) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL1493000 | 0.82 | TDP1 (0.48) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL24453243 | 0.79 | ALDH1A1 (0.35) | TDP1CYP3A4KDM1AKDM1BALDH1A1 | |
| SCHEMBL7931545 | 0.77 | TDP1 (0.45) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL9730127 | 0.75 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL9730202 | 0.74 | ALDH1A1 (0.47) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0241559-A1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-10-21 | — | — | EP | disclosed |