Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411365 | 0.88 | — | — | |
| Iodide SCHEMBL614910 | 0.88 | — | — | |
| Bromide SCHEMBL2818240 | 0.88 | — | — | |
| SCHEMBL9847825 | 0.88 | — | — | |
| SCHEMBL4681983 | 0.88 | ALDH1A1 (0.75) | — | |
| SCHEMBL1319 | 0.87 | — | — | |
| SCHEMBL15658212 | 0.87 | ALDH1A1 (1.00) | — | |
| Hydrochloric Acid SCHEMBL7512029 | 0.80 | — | — | |
| SCHEMBL8715381 | 0.80 | — | — | |
| Water SCHEMBL8878056 | 0.80 | ALDH1A1 (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454095-B | Acylphosphino-oxygen compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-115974921-A | Method for synthesizing tenofovir | 浙江嘉化新材料有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20220106340-A1 | ACYLPHOSPHINE OXIDE COMPOUNDS AND PREPARATION METHODS THEREOF | ANHUI CHICHEM CORPORATION (CN) | 2022-04-07 | — | — | US | claimed |
| EP-3892625-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | Anqing Lighting Optoelectronics Technology Co., Ltd (CN) | 2021-10-13 | — | — | EP | claimed |
| CN-113454095-A | Acylphosphinoxide compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2021-09-28 | — | — | CN | claimed |
| WO-2020113585-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | 安庆莱霆光电科技有限公司 | 2020-06-11 | — | — | WO | claimed |
| CN-113454095-B | Acylphosphino-oxygen compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-115974921-A | Method for synthesizing tenofovir | 浙江嘉化新材料有限公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20220106340-A1 | ACYLPHOSPHINE OXIDE COMPOUNDS AND PREPARATION METHODS THEREOF | ANHUI CHICHEM CORPORATION (CN) | 2022-04-07 | — | — | US | disclosed |
| EP-3892625-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | Anqing Lighting Optoelectronics Technology Co., Ltd (CN) | 2021-10-13 | — | — | EP | disclosed |
| CN-113454095-A | Acylphosphinoxide compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020113585-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | 安庆莱霆光电科技有限公司 | 2020-06-11 | — | — | WO | disclosed |
| US-4992584-A | Using homogeneous solution of 1,3-dioxin-4-one and a,b-unsaturated amide | EASTMAN KODAK COMPANY (US) | 1991-02-12 | — | — | US | disclosed |