Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17129799 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL246666 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4TDP1 | |
| SCHEMBL18039295 | 0.76 | EPHX1 (0.38) | ALDH1A1ALOX15CYP3A4TDP1 | |
| SCHEMBL9342143 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL21247079 | 0.75 | ALDH1A1 (0.51) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL11855453 | 0.75 | ALDH1A1 (0.42) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL16863842 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL9410683 | 0.74 | ALDH1A1 (0.45) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL9410641 | 0.74 | ALDH1A1 (0.45) | ALDH1A1ALOX15CYP3A4TDP1KDM4E | |
| SCHEMBL9410694 | 0.74 | ALDH1A1 (0.45) | ALDH1A1ALOX15CYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260472-B1 | METHOD FOR THE PRODUCTION OF CYCLOALIPHATIC KETONES | FIRMENICH SA (CH) | 1991-03-13 | — | — | EP | disclosed |
| US-4900870-A | Process for the preparation of cycloaliphatic ketones | FIRMENICH S.A. (CH) | 1990-02-13 | — | — | US | disclosed |
| EP-0260472-A2 | Method for the production of cycloaliphatic ketones | FIRMENICH SA (CH) | 1988-03-23 | — | — | EP | disclosed |