Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836996 | 0.82 | MAOA (0.48) | MAPK14TERTMAOBMAOAMAPT | |
| SCHEMBL9835174 | 0.81 | MAPK14 (0.38) | MAPK14TERTMAOBMAOAMAPT | |
| SCHEMBL10702160 | 0.80 | HTR2B (0.40) | HTR2AMAPTKDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9835660 | 0.79 | MAPK14 (0.37) | MAPK14TERTMAOBMAOAMAPT | |
| SCHEMBL8797926 | 0.77 | MAPK14 (0.33) | MAPK14TERTMAOBMAOAMAPT | |
| SCHEMBL8797476 | 0.76 | MAPT (0.43) | MAPK14TERTMAOBMAOAMAPT | |
| SCHEMBL1367244 | 0.75 | HTR2A (0.57) | HTR2ATERTMAOBMAOANISCH | |
| SCHEMBL6386269 | 0.73 | HTR2A (0.50) | HTR2AP2RX7ANPEP | |
| SCHEMBL11005428 | 0.72 | CYP2D6 (0.43) | HTR2ATERTALDH1A1 | |
| SCHEMBL10700081 | 0.72 | MAPK14 (0.37) | MAPK14MAOBMAOAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| EP-0129879-A2 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |