SCHEMBL9837370

SCHEMBL9837370

NN1C=CCC(C(=O)O)=C1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PYGM P11217 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890639 0.67 PYGM (0.52) PYGM
SCHEMBL28744256 0.64 PYGM (0.34) PYGM
SCHEMBL10465191 0.61
SCHEMBL16749889 0.61
SCHEMBL10969632 0.60
SCHEMBL6752103 0.60 PYGM (0.34) PYGM
SCHEMBL15152235 0.59 PYGM (0.32) PYGM
SCHEMBL13657660 0.58
SCHEMBL4827962 0.58 PYGM (0.43) PYGM
SCHEMBL16749888 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161221-B1 PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-07-10 EP claimed
US-4748244-A HERBICIDE INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1988-05-31 US claimed
JP-60246369-A None JP disclosed
EP-0161221-B1 PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-07-10 EP disclosed
US-4748244-A HERBICIDE INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1988-05-31 US disclosed
US-4748244-A HERBICIDE INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1988-05-31 US disclosed
US-4748244-A HERBICIDE INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1988-05-31 US disclosed
EP-0161221-A3 PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES 1986-11-12 EP disclosed
JP-S60246369-A MANUFACTURE OF PYRIDINE-2,3-DICARBOXYLIC ACID DERIVATIVE ANDNOVEL 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC ACID DERIVATIVE CIBA GEIGY AG 1985-12-06 JP disclosed
EP-0161221-A2 Process for the preparation of pyridine-2,3-dicarboxylic-acid derivatives and of 1-amino-1,4-dihydropyridine-2,3-dicarboxylic-acid derivatives CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed