Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136542 | 0.87 | PKM (0.62) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL5092768 | 0.84 | PKM (0.63) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL5092771 | 0.84 | PKM (0.63) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL5361025 | 0.83 | PKM (0.58) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL11624114 | 0.81 | PKM (0.62) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL20417902 | 0.79 | PKM (0.63) | PKMPOLBHPGDALDH1A1RAB9A | |
| SCHEMBL3448804 | 0.78 | CNR2 (0.57) | POLBHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL1499949 | 0.78 | CNR2 (0.57) | POLBHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL1499948 | 0.78 | CNR2 (0.57) | POLBHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13428947 | 0.78 | PKM (0.70) | PKMPOLBHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304778-B1 | PROCESS FOR THE PRODUCTION OF N-ACYLATED MERCAPTO-ALPHA-AMINO ACIDS | Degussa Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-4918223-A | Method of preparing N-acylated mercapto-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1990-04-17 | — | — | US | disclosed |
| EP-0304778-A1 | Process for the production of N-acylated mercapto-alpha-amino acids | Degussa Aktiengesellschaft (DE) | 1989-03-01 | — | — | EP | disclosed |