SCHEMBL9837586

SCHEMBL9837586

CCCC/C=C(\CCCCC)C(O)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.40
P2RY10 O00398 1/20 0.39
GPR174 Q9BXC1 1/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
FAAH O00519 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ASAH2 Q9NR71 1/20 0.38
ABCB1 P08183 1/20 0.38
DGKA P23743 1/20 0.38
POLB P06746 1/20 0.38
POLA1 P09884 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
FABP3 P05413 2/20 0.38
LPAR1 Q92633 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837589 1.00 MAPT (0.42) MAPTZDHHC7P2RY10GPR174LMNA
SCHEMBL9834930 0.80 CA1 (0.43) MAPTZDHHC7LMNAMEN1FAAH
SCHEMBL9834925 0.80 CA1 (0.43) MAPTZDHHC7LMNAMEN1FAAH
SCHEMBL11535355 0.78 CES2 (0.52) MAPTZDHHC7MEN1FAAHMAPK1
SCHEMBL9836703 0.77 ZDHHC7 (0.42) MAPTZDHHC7FAAHMAPK1CA1
SCHEMBL9836706 0.77 ZDHHC7 (0.42) MAPTZDHHC7FAAHMAPK1CA1
SCHEMBL9837221 0.76 CYP3A4 (0.37) ZDHHC7MEN1MAPK1KMT2ACA1
SCHEMBL9837217 0.76 CYP3A4 (0.37) ZDHHC7MEN1MAPK1KMT2ACA1
SCHEMBL14102586 0.72 EP300 (0.41) MAPTLMNAMEN1FAAHMAPK1
SCHEMBL9836443 0.71 ZDHHC7 (0.47) MAPTZDHHC7LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed