Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381588 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL2054027 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL29891066 | 0.85 | HSD17B10 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL16487171 | 0.85 | HSD17B10 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL28814531 | 0.84 | HSD17B10 (0.54) | ALDH1A1HSD17B10CYP1A2HPGDTHRB | |
| SCHEMBL6863260 | 0.83 | SIRT2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDACHE | |
| SCHEMBL29357296 | 0.83 | SIRT2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDACHE | |
| SCHEMBL31610342 | 0.83 | SIRT2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDACHE | |
| SCHEMBL14912 | 0.83 | SIRT2 (0.50) | ALDH1A1HSD17B10CYP1A2HPGDACHE | |
| SCHEMBL31192241 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200107-B1 | PROCESS FOR THE IMMOBILIZATION OF DISSOLVED PROTEINS | RÖHM GMBH (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0200107-A2 | Process for the immobilization of dissolved proteins | RÖHM GMBH (DE) | 1986-11-05 | — | — | EP | disclosed |