Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | SI | P14410 | 1/20 | 0.72 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 9/20 | 0.62 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.62 |
| ▸ | IGF1R | P08069 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895175 | 0.84 | MAOA (0.57) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL30346407 | 0.84 | MGAM (1.00) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL2314333 | 0.84 | MGAM (1.00) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL28020193 | 0.83 | MGAM (0.97) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL31193506 | 0.83 | MGAM (0.74) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL9835098 | 0.83 | MGAM (0.74) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL11029982 | 0.81 | MAOA (0.72) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL1794501 | 0.80 | MAOA (0.63) | MGAMGAASIMGAM2MAOA | |
| Dimethyl Sulfoxide SCHEMBL28246380 | 0.80 | MGAM (0.83) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL5579464 | 0.79 | CLK2 (0.63) | MGAMGAASIMGAM2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |