SCHEMBL9837669

SCHEMBL9837669

CCn1c(=O)sc2cc(F)c(N=C=O)cc21

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TP53 P04637 1/20 0.33
TSHR P16473 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
GAA P10253 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
HRH1 P35367 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9478143 0.84 POLB (0.34) NPSR1
SCHEMBL9838712 0.84 SHMT2 (0.41) MAPTALDH1A1GAA
SCHEMBL30945117 0.84 SHMT2 (0.41) MAPTALDH1A1GAA
SCHEMBL9837663 0.78 CNR2 (0.36)
SCHEMBL9688013 0.78 GRIN1 (0.41)
SCHEMBL9837609 0.73 SHMT2 (0.40) MAPTALDH1A1GAA
SCHEMBL9781834 0.73 POLB (0.33) NPSR1
SCHEMBL29253095 0.71 NPC1 (0.30) MAPTSMN1; SMN2NPSR1ALDH1A1GAA
SCHEMBL9686339 0.67 GRIN1 (0.40)
SCHEMBL8931497 0.67 CNR2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230874-B1 BENZOTHIAZOLYLAZOLIDINES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-11-27 EP disclosed
US-4898948-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-02-06 US disclosed
US-4828605-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-09 US disclosed
US-4786310-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-22 US disclosed
EP-0230874-A1 Benzothiazolylazolidines, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-05 EP disclosed