Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbendazim SCHEMBL18131962 | 0.89 | METAP1 (0.65) | METAP1CYP1A2HIF1ALMNAKDR | |
| Mebendazole SCHEMBL2406875 | 0.88 | METAP1 (0.54) | METAP1CYP1A2HIF1ALMNAKDR | |
| Mebendazole SCHEMBL29409261 | 0.83 | ABL1 (0.82) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL3429179 | 0.83 | ABL1 (0.82) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL15860 | 0.83 | ABL1 (0.82) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL27690766 | 0.82 | ABL1 (0.80) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL21051200 | 0.82 | ABL1 (0.80) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL21051203 | 0.82 | ABL1 (0.80) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL17262440 | 0.82 | ABL1 (0.80) | CYP1A2HIF1ALMNAKDRALDH1A1 | |
| Mebendazole SCHEMBL28186589 | 0.82 | ABL1 (0.80) | CYP1A2HIF1ALMNAKDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | claimed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | claimed |