Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624724 | 0.83 | DBH (0.44) | GFERDBHTP53LMNAALDH1A1 | |
| SCHEMBL10399535 | 0.80 | ALDH1A1 (0.43) | DBHHTTTP53LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10399707 | 0.79 | ALDH1A1 (0.42) | DBHHTTTP53LMNAALDH1A1 | |
| SCHEMBL10511738 | 0.79 | TP53 (0.38) | DBHHTTTP53LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10399706 | 0.78 | TP53 (0.38) | DBHHTTTP53LMNAALDH1A1 | |
| SCHEMBL10425442 | 0.77 | ALDH1A1 (0.55) | HTTTP53LMNAALDH1A1MEN1 | |
| SCHEMBL7215334 | 0.77 | MEN1 (0.60) | HTTLMNAALDH1A1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10424921 | 0.76 | ALDH1A1 (0.54) | HTTTP53LMNAALDH1A1MEN1 | |
| SCHEMBL10621243 | 0.76 | GFER (0.43) | GFERTP53LMNAALDH1A1MEN1 | |
| SCHEMBL10512073 | 0.76 | POLB (0.41) | HTTTP53LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992459-A | Hypotensive agents, antiulcer agents | SMITHKLINE BEECHAM CORPORATION (US) | 1991-02-12 | — | — | US | claimed |