Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839473 | 1.00 | KDM4E (0.66) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL9839479 | 1.00 | KDM4E (0.66) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL9838120 | 0.97 | KDM4E (0.61) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL9838123 | 0.97 | KDM4E (0.61) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL8675617 | 0.85 | MAOB (0.60) | MAOBGSK3BBACE1RAB9ASMN1; SMN2 | |
| SCHEMBL8675616 | 0.85 | MAOB (0.60) | MAOBGSK3BBACE1RAB9ASMN1; SMN2 | |
| SCHEMBL8676691 | 0.85 | MAOB (0.60) | MAOBGSK3BBACE1RAB9ASMN1; SMN2 | |
| SCHEMBL8049689 | 0.85 | MAPT (0.85) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL8049692 | 0.85 | MAPT (0.85) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL1304425 | 0.85 | MAPT (0.85) | KDM4EMAPTALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |